We demonstrate the utilization of an interferometrically created nanoporous polymeric gratings as a platform for biosensing applications. Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings was fabricated by combining holographic interference patterning and APTES-functionalization of pre-polymer syrup. The successful detection of multiple biomolecules indicates that the biofunctionalized nanoporous polymeric gratings can act as biosensing platforms which are label-free, inexpensive, and applicable as high-throughput assays.
Nanoporous Polymeric Grating-Based Biosensors
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Gao, T, Hsiao, V, Zheng, YB, & Huang, TJ. "Nanoporous Polymeric Grating-Based Biosensors." Proceedings of the ASME 2010 International Mechanical Engineering Congress and Exposition. Volume 5: Energy Systems Analysis, Thermodynamics and Sustainability; NanoEngineering for Energy; Engineering to Address Climate Change, Parts A and B. Vancouver, British Columbia, Canada. November 12–18, 2010. pp. 1453-1456. ASME. https://doi.org/10.1115/IMECE2010-40928
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