Joint simulators have been used frequently to generate meaningful data on prosthetic wear, bone kinematics, and ligament function. The complex and high loads associated with the knee joint have prompted the development of a wide variety of knee simulators. A four-axis knee simulator was developed at Purdue University that simulates the tibio-femoral and patello-femoral forces by four externally applied loads at the hip and ankle at the hip and ankle. The Purdue Knee Simulator has repeatedly demonstrated the ability to generate realistic prosthetic wear and kinematic motions similar to the natural knee. The operation of the Purdue Knee Simulator, the generation of input profiles, and a brief review of some of the research completed utilizing this machine is presented.

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