The mechanical properties of collagenous tissues are known to depend on a wide variety of factors, such as the type of tissue and the composition of its extracellular matrix. Relating mechanical roles to individual matrix components in such a complex system is difficult, if not impossible. However, as collagen is the main load bearing component in connective tissues, the relation between collagen and tissue biomechanics has been studied extensively in various types of tissues. The type of collagen, the amount and type of inter- and intramolecular covalent cross-links and collagen fibril morphology are involved in the tissues mechanical behavior (Beekman et al., 1997; Parry et al., 1978; Avery and Bailey, 2005). From literature it is known that the the collagen fibril diameter distribution can be directly related to the mechanical properties of the tissue. In particular, the diameter distribution of collagen fibrils is largely determined by the tissues requirement for tensile strength and elasticity (Parry et al., 1978).
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ASME 2007 Summer Bioengineering Conference
June 20–24, 2007
Keystone, Colorado, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
0-7918-4798-5
PROCEEDINGS PAPER
Stress Dependent Collagen Fibril Diameter Distribution in Human Aortic Valves
Angelique Balguid,
Angelique Balguid
Eindhoven University of Technology, The Netherlands
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Anita Mol,
Anita Mol
Eindhoven University of Technology, The Netherlands
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Niels Driessen,
Niels Driessen
Eindhoven University of Technology, The Netherlands
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Carlijn Bouten,
Carlijn Bouten
Eindhoven University of Technology, The Netherlands
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Frank Baaijens
Frank Baaijens
Eindhoven University of Technology, The Netherlands
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Angelique Balguid
Eindhoven University of Technology, The Netherlands
Anita Mol
Eindhoven University of Technology, The Netherlands
Niels Driessen
Eindhoven University of Technology, The Netherlands
Carlijn Bouten
Eindhoven University of Technology, The Netherlands
Frank Baaijens
Eindhoven University of Technology, The Netherlands
Paper No:
SBC2007-175644, pp. 145-146; 2 pages
Published Online:
March 12, 2014
Citation
Balguid, A, Mol, A, Driessen, N, Bouten, C, & Baaijens, F. "Stress Dependent Collagen Fibril Diameter Distribution in Human Aortic Valves." Proceedings of the ASME 2007 Summer Bioengineering Conference. ASME 2007 Summer Bioengineering Conference. Keystone, Colorado, USA. June 20–24, 2007. pp. 145-146. ASME. https://doi.org/10.1115/SBC2007-175644
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