Sub-ablative heating of collagenous soft tissues is central to thermal therapies such as thermal capsulorrhaphy, thermokeratoplasty and skin resurfacing . These therapies target the heat-induced denaturation of the collagen molecule, which starts in a temperature range of 55–75 °C. There are relatively few theoretical studies describing the heat-induced alterations in soft tissues, which are mainly phenomenological . In this work, a methodology for studying the kinetics of soft tissue thermomechanics is presented and used to predict the thermal response of New Zealand white patellar tendons . The modeling approach accounts for the microstructure of the tissue and utilizes information at the single-molecule level to obtain the macroscopic response.
A Structural, Kinetic Model of Soft Tissue Thermomechanics
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Stylianopoulos, T, Aksan, A, & Barocas, VH. "A Structural, Kinetic Model of Soft Tissue Thermomechanics." Proceedings of the ASME 2007 Summer Bioengineering Conference. ASME 2007 Summer Bioengineering Conference. Keystone, Colorado, USA. June 20–24, 2007. pp. 331-332. ASME. https://doi.org/10.1115/SBC2007-176008
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