Arteriovenous (AV) fistula failure is a major clinical problem for the 350,000 patients currently on hemodialysis in the United States. The reasons for this failure are mainly attributed to venous stenosis due to neointimal hyperplasia together with a possible failure of vascular dilatation . Despite the magnitude of the clinical problem, there are currently no effective therapies for AV fistula failure. We believe that this is due to a lack of knowledge about the mechanisms involved in both neointimal hyperplasia and vascular dilatation in the specific context of AV fistulae.
- Bioengineering Division
Vascular Remodeling of Arteriovenous Fistula
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Krishnamoorthy, MK, Roy-Chaudhury, P, Wang, Y, Holland, CK, Rigger, D, Choe, A, & Banerjee, RK. "Vascular Remodeling of Arteriovenous Fistula." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 1077-1078. ASME. https://doi.org/10.1115/SBC2009-206508
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