Large Eddy Simulation of Steady and Pulsating Flow in Asymmetric Stenosed Pipe

Local hemodynamics and its impact on the development of cardiovascular disease and the blood itself have gained increasing attention during the last decades. Regions with low and/or oscillatory Wall Shear Stress (WSS) have been correlated with increased risk for development of atherosclerosis [1]; and turbulence in the cardio vascular system is suggested to increase the risk for hemolysis as well as platelet activation and thrombus formation [2, 3]. Furthermore, turbulent flows are inherently oscillatory with large spatial as well as temporal fluctuation, and hence possibly a risk for atherosclerosis development per se.