Traumatic Brain Injuries (TBI) affect up to 1.5 million people annually within the United States with as many as 250,000 being hospitalized and 50,000 dying . TBI events occur when the brain experiences a sudden trauma such as a rapid deceleration of the brain that typically occurs during motor vehicle accidents. During rapid deceleration events, the brain is subjected to high inertial forces that can result in a shearing or elongation of axons that is commonly known as Diffuse Axonal Injury (DAI) [2,3].
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Simulating Axonal Stretch During Traumatic Brain Injury Events
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Dollé, J, Barminko, J, Schloss, R, & Yarmush, ML. "Simulating Axonal Stretch During Traumatic Brain Injury Events." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 921-922. ASME. https://doi.org/10.1115/SBC2010-19653
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