Computational simulations of brain injury mechanisms have advanced to a level of sophistication where in addition to capturing different anatomic regions, the computational mesh is capable of distinguishing white and grey matter in the brain. Brain tissue is typically modeled as an isotropic, viscoelastic material. Experiments have shown that the mechanical response of brain tissue to an external load varies depending on the location from which the tissue is harvested and also the direction of loading. Some researchers have developed anisotropic constitutive models by appealing to the composite material case wherein cylindrical axon fibers are immersed in a cellular matrix. Though such material models have been developed over a small sample, they have not been applied over the entire brain for simulation purposes.
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ASME 2011 Summer Bioengineering Conference
June 22–25, 2011
Farmington, Pennsylvania, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-5458-7
PROCEEDINGS PAPER
Development of a Biofidelic Material Model for Brain Tissue
Sandeep Kulathu,
Sandeep Kulathu
University of Alabama at Birmingham, Birmingham, AL
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David L. Littlefield
David L. Littlefield
University of Alabama at Birmingham, Birmingham, AL
Search for other works by this author on:
Sandeep Kulathu
University of Alabama at Birmingham, Birmingham, AL
David L. Littlefield
University of Alabama at Birmingham, Birmingham, AL
Paper No:
SBC2011-53136, pp. 77-78; 2 pages
Published Online:
July 17, 2013
Citation
Kulathu, S, & Littlefield, DL. "Development of a Biofidelic Material Model for Brain Tissue." Proceedings of the ASME 2011 Summer Bioengineering Conference. ASME 2011 Summer Bioengineering Conference, Parts A and B. Farmington, Pennsylvania, USA. June 22–25, 2011. pp. 77-78. ASME. https://doi.org/10.1115/SBC2011-53136
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