Calcific aortic valve disease affects a wide range of the population in the United States. Each year there are approximately 50,000 valve replacements due to this disease [(Freeman & Otto, 2005)]. While it is unclear what the exact causes of CAVD are, it does appear to be correlated to local hemodynamic conditions particularly related to the complex spatio-temporal nature of fluid wall shear stress dynamics that the aortic side of the leaflets experience.
- Bioengineering Division
Aortic Valve Sinus Vorticity Dynamics and the Potential Role of Coronary Flow
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Moore, BL, & Dasi, LP. "Aortic Valve Sinus Vorticity Dynamics and the Potential Role of Coronary Flow." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT04A009. ASME. https://doi.org/10.1115/SBC2013-14335
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