Radiofrequency (RF) ablation is one of the promising technologies of tumor therapy due to its minimal invasiveness and other advantages. The high frequency alternating electrical current makes movement of the intracellular ions, results in frictional heat inside the tumor tissue and local temperature rising. Temperature of the tissue near the RF electrode increases much faster than the distant part. When it reaches the vapor (boiling) point, excessive evaporation takes place and increases electrical impedance between the electrode and the targeted tissue. This has been a major obstacle for its application. Coolants such as water circulating in the electrodes has been proposed, but as the coolants are only effective on the electrode wall, quick evaporation and correspondent carbonization still exists.
- Bioengineering Division
Numerical Study of the Influence of Water Evaporation on Radiofrequency Ablation
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Zhu, Q, Ying, B, Zhang, A, & Xu, LX. "Numerical Study of the Influence of Water Evaporation on Radiofrequency Ablation." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT07A019. ASME. https://doi.org/10.1115/SBC2013-14459
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