Photopolymerization methods such as multiphoton polymerization have been used successfully to create bioactive patterned scaffolds with micron-scale resolution capable of supporting cell growth and differentiation for engineered tissue.  They have also been shown effective for fabrication of a variety of MEMS devices.  Currently, multiphoton polymerization and similar technologies require a bulky and expensive optical system based on a femto- or picosecond pulsed laser and an XYZ arrangement of high-resolution translating stages.  Such systems are currently prohibitive in both cost and effort required to assemble, calibrate, and maintain. Consolidating optical components and motors into a smaller, less-complex device may facilitate the manufacture of customized tissue engineered constructs and MEMS devices on-site in more remote locations on an as-needed basis.
- Bioengineering Division
Preliminary Fabrication Capabilities of a 2-Axis Photolithography System Based on Optical Drive Motors and Laser Diodes
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Bell, A, & Nistor, V. "Preliminary Fabrication Capabilities of a 2-Axis Photolithography System Based on Optical Drive Motors and Laser Diodes." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT20A025. ASME. https://doi.org/10.1115/SBC2013-14608
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