In this study, newly developed two-equation turbulence models and transitional variants are employed for the prediction of blood flow patterns in a diseased carotid artery where the growth, progression, and structure of the plaque at rupture are closely linked to low and oscillating wall shear stresses. Moreover, the laminar-turbulent transition in the poststenotic zone can alter the separation zone length, wall shear stress, and pressure distribution over the plaque, with potential implications for stresses within the plaque. Following the validation with well established experimental measurements and numerical studies, a magnetic-resonance (MR) image-based model of the carotid bifurcation with 70% stenosis was reconstructed and simulated using realistic patient-specific conditions. Laminar flow, a correlation-based transitional version of Menter’s hybrid shear stress transport (SST) model and its “scale adaptive simulation” (SAS) variant were implemented in pulsatile simulations from which analyses of velocity profiles, wall shear stress, and turbulence intensity were conducted. In general, the transitional version of SST and its SAS variant are shown to give a better overall agreement than their standard counterparts with experimental data for pulsatile flow in an axisymmetric stenosed tube. For the patient-specific case reported, the wall shear stress analysis showed discernable differences between the laminar flow and SST transitional models but virtually no difference between the SST transitional model and its SAS variant.
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December 2008
Research Papers
Analysis of Flow Disturbance in a Stenosed Carotid Artery Bifurcation Using Two-Equation Transitional and Turbulence Models
F. P. P. Tan,
F. P. P. Tan
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
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G. Soloperto,
G. Soloperto
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
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S. Bashford,
S. Bashford
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
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N. B. Wood,
N. B. Wood
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
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S. Thom,
S. Thom
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
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A. Hughes,
A. Hughes
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
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X. Y. Xu
X. Y. Xu
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
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F. P. P. Tan
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
G. Soloperto
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
S. Bashford
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
N. B. Wood
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UK
S. Thom
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
A. Hughes
National Heart and Lung Institute, International Centre for Circulatory Health,
Imperial College London
, 59-61 North Wharf Road, Paddington, London, W2 1LA, UK
X. Y. Xu
Department of Chemical Engineering,
Imperial College London
, South Kensington Campus, London, SW7 2AZ, UKJ Biomech Eng. Dec 2008, 130(6): 061008 (12 pages)
Published Online: October 10, 2008
Article history
Received:
October 5, 2007
Revised:
March 1, 2008
Published:
October 10, 2008
Citation
Tan, F. P. P., Soloperto, G., Bashford, S., Wood, N. B., Thom, S., Hughes, A., and Xu, X. Y. (October 10, 2008). "Analysis of Flow Disturbance in a Stenosed Carotid Artery Bifurcation Using Two-Equation Transitional and Turbulence Models." ASME. J Biomech Eng. December 2008; 130(6): 061008. https://doi.org/10.1115/1.2978992
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