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Journal Articles

Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells

Yago Juste-Lanas, Pedro Enrique Guerrero, Daniel Camacho-Gómez, Silvia Hervás-Raluy, Jose M. García-Aznar, María J. Gomez-Benito

J Biomech Eng. July 2022, 144(7): 074502.

Paper No: BIO-21-1259

DOI: https://doi.org/10.1115/1.4053143

Published Online: February 15, 2022

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Topics: Cancer, Microfluidics, Tumors

Includes: Supplementary data

Journal Articles

A Microfluidic System to Measure Neonatal Lung Compliance Over Late Stage Development as a Functional Measure of Lung Tissue Mechanics

Laurel E. Schappell, Daniel J. Minahan, Jason P. Gleghorn

J Biomech Eng. October 2020, 142(10): 100803.

Paper No: BIO-19-1556

DOI: https://doi.org/10.1115/1.4047133

Published Online: August 31, 2020

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Topics: Lung, Biological tissues, Microfluidics, Pressure, Calibration

Journal Articles

Internal Viscosity-Dependent Margination of Red Blood Cells in Microfluidic Channels

Faisal Ahmed, Marmar Mehrabadi, Zixiang Liu, Gilda A. Barabino, Cyrus K. Aidun

J Biomech Eng. June 2018, 140(6): 061013.

Paper No: BIO-17-1250

DOI: https://doi.org/10.1115/1.4039897

Published Online: April 30, 2018

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Topics: Erythrocytes, Flow (Dynamics), Microfluidics, Shear rate, Simulation, Viscosity, Deformation, Equilibrium (Physics)

Includes: Supplementary data

Journal Articles

Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment

Adnan Morshed, Prashanta Dutta

J Biomech Eng. January 2018, 140(1): 011009.

Paper No: BIO-17-1090

DOI: https://doi.org/10.1115/1.4037915

Published Online: November 9, 2017

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Topics: Biological tissues, Microfluidics, Oxygen, Cancer

Includes: Supplementary data

Journal Articles

2016 Summer Biomechanics, Bioengineering, and Biotransport Conference Student Paper Competition

J Biomech Eng. February 2017, 139(2): 020207.

Paper No: BIO-16-1523

DOI: https://doi.org/10.1115/1.4035643

Published Online: January 19, 2017

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Topics: Bioengineering, Biological tissues, Biomaterials, Biomechanics, Biotransport, Diseases, Fluids, Heat transfer, Human dynamics, Imaging

Journal Articles

In Vitro Evaluation of the Link Between Cell Activation State and Its Rheological Impact on the Microscale Flow of Neutrophil Suspensions

Michael L. Akenhead, Nolan M. Horrall, Dylan Rowe, Palaniappan Sethu, Hainsworth Y. Shin

J Biomech Eng. September 2015, 137(9): 091003.

Paper No: BIO-14-1569

DOI: https://doi.org/10.1115/1.4030824

Published Online: September 1, 2015

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Topics: Erythrocytes, Flow (Dynamics), Rheology, Microscale devices, Microfluidics, Viscosity, Leukocytes

Journal Articles

Dynamics of Interstitial Fluid Pressure in Extracellular Matrix Hydrogels in Microfluidic Devices

Joe Tien, Le Li, Ozgur Ozsun, Kamil L. Ekinci

J Biomech Eng. September 2015, 137(9): 091009.

Paper No: BIO-15-1152

DOI: https://doi.org/10.1115/1.4031020

Published Online: July 22, 2015

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Topics: Dynamics (Mechanics), Fluid pressure, Microfluidics, Plasma desorption mass spectrometry, Pressure, Diffusion (Physics), Permeability, Scaling laws (Mathematical physics)

Includes: Supplementary data

Journal Articles

Device-Based In Vitro Techniques for Mechanical Stimulation of Vascular Cells: A Review

Caleb A. Davis, Steve Zambrano, Pratima Anumolu, Alicia C. B. Allen, Leonardo Sonoqui, Michael R. Moreno

J Biomech Eng. April 2015, 137(4): 040801.

Paper No: BIO-13-1508

DOI: https://doi.org/10.1115/1.4029016

Published Online: April 1, 2015

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Topics: Flow (Dynamics), Pressure, Shear stress, Vessels, Microfluidics, Fluids

Journal Articles

Design of a Microfluidic System for Red Blood Cell Aggregation Investigation

R. Mehri, C. Mavriplis, M. Fenech

J Biomech Eng. June 2014, 136(6): 064501.

Paper No: BIO-13-1317

DOI: https://doi.org/10.1115/1.4027351

Published Online: April 18, 2014

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Topics: Blood, Design, Erythrocytes, Flow (Dynamics), Fluids, Microchannels, Microfluidics, Plasmas (Ionized gases), Shear rate, Computer simulation

Journal Articles

Transport of Dynamic Biochemical Signals in Steady Flow in a Shallow Y-Shaped Microfluidic Channel: Effect of Transverse Diffusion and Longitudinal Dispersion

Yong-Jiang Li, Yizeng Li, Tun Cao, Kai-Rong Qin

J Biomech Eng. December 2013, 135(12): 121011.

Paper No: BIO-13-1063

DOI: https://doi.org/10.1115/1.4025774

Published Online: November 12, 2013

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Topics: Diffusion (Physics), Flow (Dynamics), Signals, Transfer functions, Microfluidics

Journal Articles

Investigation of Hydrodynamic Focusing in a Microfluidic Coulter Counter Device

Muheng Zhang, Yongsheng Lian, Cindy Harnett, Ellen Brehob

J Biomech Eng. August 2012, 134(8): 081001.

DOI: https://doi.org/10.1115/1.4007091

Published Online: August 6, 2012

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Topics: Flow (Dynamics), Microfluidics, Microchannels, Diffusion (Physics), Fluids

Journal Articles

A Porous Elastic Model for Bacterial Biofilms: Application to the Simulation of Deformation of Bacterial Biofilms Under Microfluidic Jet Impingement

Leo Y. Zheng, Dylan S. Farnam, Dorel Homentcovschi, Bahgat G. Sammakia

J Biomech Eng. May 2012, 134(5): 051003.

DOI: https://doi.org/10.1115/1.4006683

Published Online: May 25, 2012

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Topics: Computer simulation, Deformation, Flow (Dynamics), Fluid structure interaction, Fluids, Microfluidics, Nozzles, Porous materials, Reynolds number, Shear stress

Journal Articles

Volumetric Stress-Strain Analysis of Optohydrodynamically Suspended Biological Cells

Sean S. Kohles, Yu Liang, Asit K. Saha

J Biomech Eng. January 2011, 133(1): 011004.

DOI: https://doi.org/10.1115/1.4002939

Published Online: December 22, 2010

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Topics: Biological cells, Biomechanics, Stress, Microfluidics, Flow (Dynamics)

Journal Articles

A Microfluidic Device to Establish Concentration Gradients Using Reagent Density Differences

Qingjun Kong, Richard A. Able, Jr., Veronica Dudu, Maribel Vazquez

J Biomech Eng. December 2010, 132(12): 121012.

DOI: https://doi.org/10.1115/1.4002797

Published Online: November 16, 2010

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Topics: Bridges (Structures), Diffusion (Physics), Flow (Dynamics), Manufacturing, Microchannels, Microfluidics, Plasma desorption mass spectrometry, Density, Design, Microfabrication

Journal Articles

Mechanical Stress Analysis of Microfluidic Environments Designed for Isolated Biological Cell Investigations

Sean S. Kohles, Nathalie Nève, Jeremiah D. Zimmerman, Derek C. Tretheway

J Biomech Eng. December 2009, 131(12): 121006.

DOI: https://doi.org/10.1115/1.4000121

Published Online: November 10, 2009

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Topics: Flow (Dynamics), Fluids, Stress, Gravity (Force), Microfluidics, Shear (Mechanics), Microchannel flow

Journal Articles

A Microfluidic Manipulator for Enrichment and Alignment of Moving Cells and Particles

Hsiu-hung Chen, Bingbing Sun, Kenny K. Tran, Hong Shen, Dayong Gao

J Biomech Eng. July 2009, 131(7): 074505.

DOI: https://doi.org/10.1115/1.3127258

Published Online: June 4, 2009

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Topics: Microfluidics, Particulate matter, Flow (Dynamics)

Journal Articles

Numerical Characterization of Diffusion-Based Extraction in Cell-Laden Flow Through a Microfluidic Channel

K. K. Fleming, E. K. Longmire, A. Hubel

J Biomech Eng. October 2007, 129(5): 703–711.

DOI: https://doi.org/10.1115/1.2768373

Published Online: December 11, 2006

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Topics: Diffusion (Physics), Flow (Dynamics), Permeability, Microfluidics, Design, Fluids, Cell membranes

Journal Articles

Neuro-Genetic Optimization of Temperature Control for a Continuous Flow Polymerase Chain Reaction Microdevice

Hing Wah Lee, Parthiban Arunasalam, William P. Laratta, Kankanhalli N. Seetharamu, Ishak A. Azid

J Biomech Eng. August 2007, 129(4): 540–547.

DOI: https://doi.org/10.1115/1.2746376

Published Online: December 11, 2006

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Topics: Artificial neural networks, Chain, Finite element analysis, Flow (Dynamics), Fluids, Genetic algorithms, Optimization, Simulation, Temperature, Temperature control

Journal Articles

Molding of Deep Polydimethylsiloxane Microstructures for Microfluidics and Biological Applications

A. Folch, A. Ayon, O. Hurtado, M. A. Schmidt, M. Toner

J Biomech Eng. February 1999, 121(1): 28–34.

DOI: https://doi.org/10.1115/1.2798038

Published Online: February 1, 1999

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Topics: Microfluidics, Molding, Plasma desorption mass spectrometry, Silicon-on-insulator, Microfabrication, Semiconductor wafers, Biological tissues, Etching, Mechanical stability, Particle spin

Journal Articles

Contoured Elastic-Membrane Microvalves for Microfluidic Network Integration

A. M. Young, T. M. Bloomstein, S. T. Palmacci

J Biomech Eng. February 1999, 121(1): 2–6.

DOI: https://doi.org/10.1115/1.2798039

Published Online: February 1, 1999

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Topics: Membranes, Microfluidics, Flow (Dynamics), Valves, Cavitation, Deflection, Etching, Fluids, Lasers, Manifolds

Journal citation

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Supplemental Material

Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells

A Microfluidic System to Measure Neonatal Lung Compliance Over Late Stage Development as a Functional Measure of Lung Tissue Mechanics

Internal Viscosity-Dependent Margination of Red Blood Cells in Microfluidic Channels

Mathematical Model for Tissue-Level Hypoxic Response in Microfluidic Environment

2016 Summer Biomechanics, Bioengineering, and Biotransport Conference Student Paper Competition

In Vitro Evaluation of the Link Between Cell Activation State and Its Rheological Impact on the Microscale Flow of Neutrophil Suspensions

Dynamics of Interstitial Fluid Pressure in Extracellular Matrix Hydrogels in Microfluidic Devices

Device-Based In Vitro Techniques for Mechanical Stimulation of Vascular Cells: A Review

Design of a Microfluidic System for Red Blood Cell Aggregation Investigation

Transport of Dynamic Biochemical Signals in Steady Flow in a Shallow Y-Shaped Microfluidic Channel: Effect of Transverse Diffusion and Longitudinal Dispersion

Investigation of Hydrodynamic Focusing in a Microfluidic Coulter Counter Device

A Porous Elastic Model for Bacterial Biofilms: Application to the Simulation of Deformation of Bacterial Biofilms Under Microfluidic Jet Impingement

Volumetric Stress-Strain Analysis of Optohydrodynamically Suspended Biological Cells

A Microfluidic Device to Establish Concentration Gradients Using Reagent Density Differences

Mechanical Stress Analysis of Microfluidic Environments Designed for Isolated Biological Cell Investigations

A Microfluidic Manipulator for Enrichment and Alignment of Moving Cells and Particles

Numerical Characterization of Diffusion-Based Extraction in Cell-Laden Flow Through a Microfluidic Channel

Neuro-Genetic Optimization of Temperature Control for a Continuous Flow Polymerase Chain Reaction Microdevice

Molding of Deep Polydimethylsiloxane Microstructures for Microfluidics and Biological Applications

Contoured Elastic-Membrane Microvalves for Microfluidic Network Integration

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