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Journal Articles

Simulating Subject-Specific Aortic Hemodynamic Effects of Valvular Lesions in Rheumatic Heart Disease

Hannah L. Cebull, Olukayode O. Aremu, Radhika S. Kulkarni, Samuel X. Zhang, Petronella Samuels, Stephen Jermy, Ntobeko A.B. Ntusi, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111003.
Paper No: BIO-23-1101
https://doi.org/10.1115/1.4063000
Published Online: August 2, 2023
View Article titled, Simulating Subject-Specific Aortic Hemodynamic Effects of Valvular Lesions in Rheumatic Heart Disease
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Topics: Aorta, Blood flow, Computational fluid dynamics, Diseases, Flow (Dynamics), Hemodynamics, Shear (Mechanics), Shear stress, Simulation, Statistical analysis
Includes: Supplementary data
Journal Articles

A Computational Study of Dynamic Obstruction in Type B Aortic Dissection

T. Kim, P. A. J. van Bakel, N. Nama, N. Burris, H. J. Patel, D. M. Williams, C. A. Figueroa
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2023, 145(3): 031008.
Paper No: BIO-22-1176
https://doi.org/10.1115/1.4056355
Published Online: December 21, 2022
View Article titled, A Computational Study of Dynamic Obstruction in Type B Aortic Dissection
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Topics: Blood, Flow (Dynamics), Pressure, Simulation, Displacement, Hemodynamics, Vessels, Aorta, Boundary-value problems
Journal Articles

Comparative Assessment of Biomechanical Parameters in Subjects With Multiple Cerebral Aneurysms Using Fluid–Structure Interaction Simulations

Tanmay C. Shidhore, Aaron A. Cohen-Gadol, Vitaliy L. Rayz, Ivan C. Christov
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2023, 145(5): 051003.
Paper No: BIO-22-1154
https://doi.org/10.1115/1.4056317
Published Online: December 21, 2022
View Article titled, Comparative Assessment of Biomechanical Parameters in Subjects With Multiple Cerebral Aneurysms Using Fluid–Structure Interaction Simulations
Open the PDF for Comparative Assessment of Biomechanical Parameters in Subjects With Multiple Cerebral Aneurysms Using Fluid–Structure Interaction Simulations in another window
Topics: Aneurysms, Simulation, Fluid structure interaction, Biomechanics, Stress, Flow (Dynamics), Boundary-value problems, Displacement, Vessels, Shear (Mechanics)
Includes: Supplementary data
Journal Articles

A Novel Patient-Specific Computational Fluid Dynamics Study of the Activation of Primary Collateral Pathways in the Circle of Willis During Vasospasm

Angela Straccia, Fanette Chassagne, David I. Bass, Guilherme Barros, Daniel F. Leotta, Florence Sheehan, Deepak Sharma, Michael R. Levitt, Alberto Aliseda
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041008.
Paper No: BIO-22-1155
https://doi.org/10.1115/1.4055813
Published Online: December 5, 2022
View Article titled, A Novel Patient-Specific Computational Fluid Dynamics Study of the Activation of Primary Collateral Pathways in the Circle of Willis During Vasospasm
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Topics: Computational fluid dynamics, Flow (Dynamics), Vessels, Simulation, Sensitivity analysis
Includes: Supplementary data
Journal Articles

svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies

Jonathan Pham, Sofia Wyetzner, Martin R. Pfaller, David W. Parker, Doug L. James, Alison L. Marsden
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2023, 145(3): 031001.
Paper No: BIO-22-1143
https://doi.org/10.1115/1.4056055
Published Online: December 5, 2022
View Article titled, svMorph: Interactive Geometry-Editing Tools for Virtual Patient-Specific Vascular Anatomies
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Topics: Aneurysms, Engineering simulation, Geometry, Hemodynamics, Shapes, Simulation, Deformation, Aorta, Computational fluid dynamics, Modeling
Journal Articles

Feasibility of Vascular Parameter Estimation for Assessing Hypertensive Pregnancy Disorders

Georgios Kissas, Eileen Hwuang, Elizabeth W. Thompson, Nadav Schwartz, John A. Detre, Walter R. Witschey, Paris Perdikaris
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121011.
Paper No: BIO-22-1060
https://doi.org/10.1115/1.4055679
Published Online: October 28, 2022
View Article titled, Feasibility of Vascular Parameter Estimation for Assessing Hypertensive Pregnancy Disorders
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Topics: Aorta, Flow (Dynamics), Magnetic resonance imaging, Pressure, Vessels, Waves, Geometry, Algorithms
Journal Articles

Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis

Li Changsheng, Feng Haiquan, Wang Kun, Wang Xiaotian, Wang Yonggang
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011013.
Paper No: BIO-21-1445
https://doi.org/10.1115/1.4055307
Published Online: September 19, 2022
View Article titled, Influence of the Anatomical Structure on the Hemodynamics of Iliac Vein Stenosis
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Topics: Blood flow, Hemodynamics, Particulate matter, Shear stress, Vessels, Shear (Mechanics), Blood vessels, Flow (Dynamics), Computational fluid dynamics, Thrombosis
Journal Articles

A Mathematical Model of Maladaptive Inward Eutrophic Remodeling of Muscular Arteries in Hypertension

Alexander Rachev, Tarek Shazly
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011012.
Paper No: BIO-22-1072
https://doi.org/10.1115/1.4055109
Published Online: September 1, 2022
View Article titled, A Mathematical Model of Maladaptive Inward Eutrophic Remodeling of Muscular Arteries in Hypertension
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Topics: Hoop stress, Pressure, Stress, Vessels, Dimensions, Wall thickness
Journal Articles

Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms

Christian J. Mandrycky, Ashley N. Abel, Samuel Levy, Laurel M. Marsh, Fanette Chassagne, Venkat K. Chivukula, Sari E. Barczay, Cory M. Kelly, Louis J. Kim, Alberto Aliseda, Michael R. Levitt, Ying Zheng
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. January 2023, 145(1): 011001.
Paper No: BIO-21-1298
https://doi.org/10.1115/1.4054981
Published Online: August 19, 2022
View Article titled, Endothelial Responses to Curvature-Induced Flow Patterns in Engineered Cerebral Aneurysms
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Topics: Aneurysms, Computational fluid dynamics, Endothelial cells, Flow (Dynamics), Hemodynamics, Proteins, Vessels, Polarization (Electricity), Polarization (Light), Polarization (Waves)
Includes: Supplementary data
Journal Articles

A New Method for Quantifying Abdominal Aortic Wall Shear Stress Using Phase Contrast Magnetic Resonance Imaging and the Womersley Solution

Elizabeth Iffrig, Lucas H. Timmins, Retta El Sayed, W. Robert Taylor, John N. Oshinski
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091011.
Paper No: BIO-21-1378
https://doi.org/10.1115/1.4054236
Published Online: April 19, 2022
View Article titled, A New Method for Quantifying Abdominal Aortic Wall Shear Stress Using Phase Contrast Magnetic Resonance Imaging and the Womersley Solution
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Topics: Computational fluid dynamics, Flow (Dynamics), Magnetic resonance imaging, Shear stress, Vessels, Image segmentation
Journal Articles

A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network

Po-Yi Lee, Yi Hua, Bryn L. Brazile, Bin Yang, Lin Wang, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061006.
Paper No: BIO-21-1403
https://doi.org/10.1115/1.4054056
Published Online: March 24, 2022
View Article titled, A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network
Open the PDF for A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network in another window
Topics: Vessels, Workflow, Imaging, Biological tissues
Journal Articles

Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice

Abhay B. Ramachandra, Nicole Mikush, Maor Sauler, Jay D. Humphrey, Edward P. Manning
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081008.
Paper No: BIO-21-1330
https://doi.org/10.1115/1.4053873
Published Online: March 11, 2022
View Article titled, Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice
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Topics: Fibers, Lung, Pressure, Pulmonary artery, Stress, Ventilation, Energy storage, Stiffness, Diseases, Vessels
Includes: Supplementary data
Journal Articles

Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation

Nikhil Vaidya, Marco Baragona, Valentina Lavezzo, Ralph Maessen, Karen Veroy
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. August 2022, 144(8): 084506.
Paper No: BIO-21-1368
https://doi.org/10.1115/1.4053909
Published Online: March 11, 2022
View Article titled, Tuning the Pennes Perfusion Rate to Model Large Vessel Cooling Effects in Hepatic Radiofrequency Ablation
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Topics: Biological tissues, Blood vessels, Cooling, Errors, Liver, Radiofrequency ablation, Vessels, Simulation, Temperature, Optimization
Journal Articles

The Effect of Three-Dimensional Whole, Major, and Small Vasculature on Mouse Brain Strain Under Both Diffuse and Focal Brain Injury Loading

Lihong Lu, Xingyu Liu, Kewei Bian, John G. Sled, Kenneth Monson, Arthur Brown, Haojie Mao
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. August 2022, 144(8): 084503.
Paper No: BIO-20-1445
https://doi.org/10.1115/1.4053664
Published Online: March 9, 2022
View Article titled, The Effect of Three-Dimensional Whole, Major, and Small Vasculature on Mouse Brain Strain Under Both Diffuse and Focal Brain Injury Loading
Open the PDF for The Effect of Three-Dimensional Whole, Major, and Small Vasculature on Mouse Brain Strain Under Both Diffuse and Focal Brain Injury Loading in another window
Topics: Brain, Traumatic brain injury, Vessels, Wounds, Materials properties, Finite element model
Journal Articles

A Strain Rate-Dependent Constitutive Model for Göttingen Minipig Cerebral Arteries

Noah Pearson, Gregory M. Boiczyk, Vivek Bhaskar Kote, Aravind Sundaramurthy, Dhananjay Radhakrishnan Subramaniam, Jose E. Rubio, Ginu Unnikrishnan, Jaques Reifman, Kenneth Monson
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081007.
Paper No: BIO-21-1392
https://doi.org/10.1115/1.4053796
Published Online: March 9, 2022
View Article titled, A Strain Rate-Dependent Constitutive Model for Göttingen Minipig Cerebral Arteries
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Topics: Biological tissues, Cerebral arteries, Constitutive equations, Deformation, Failure, Stress, Vessels
Journal Articles

Effect of Human Synovial Fluid From Osteoarthritis Patients and Healthy Individuals on Lymphatic Contractile Activity

Eleftheria Michalaki, Zhanna Nepiyushchikh, Josephine M. Rudd, Fabrice C. Bernard, Anish Mukherjee, Jay M. McKinney, Thanh N. Doan, Nick J. Willett, J. Brandon Dixon
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
Publisher: ASME
J Biomech Eng. July 2022, 144(7): 071012.
Paper No: BIO-21-1020
https://doi.org/10.1115/1.4053749
Published Online: February 24, 2022
View Article titled, Effect of Human Synovial Fluid From Osteoarthritis Patients and Healthy Individuals on Lymphatic Contractile Activity
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Topics: Fluids, Osteoarthritis, Vessels, Endothelial cells
Includes: Supplementary data
Journal Articles

Coronary Artery Stenting Affects Wall Shear Stress Topological Skeleton

Claudio Chiastra, Valentina Mazzi, Maurizio Lodi Rizzini, Karol Calò, Anna Corti, Alessandro Acquasanta, Giuseppe De Nisco, Davide Belliggiano, Enrico Cerrato, Diego Gallo, Umberto Morbiducci
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061002.
Paper No: BIO-21-1362
https://doi.org/10.1115/1.4053503
Published Online: February 15, 2022
View Article titled, Coronary Artery Stenting Affects Wall Shear Stress Topological Skeleton
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Topics: Computational fluid dynamics, Coronary arteries, Design, Shear stress, Stents, Topology, Hemodynamics, Flow (Dynamics), Vessels
Includes: Supplementary data
Journal Articles

Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling

John F. Eberth, Jay D. Humphrey
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. April 2022, 144(4): 044503.
Paper No: BIO-21-1188
https://doi.org/10.1115/1.4052888
Published Online: December 15, 2021
View Article titled, Reduced Smooth Muscle Contractile Capacity Facilitates Maladaptive Arterial Remodeling
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Topics: Carotid arteries, Muscle, Pressure, Stress, Wall thickness, Stiffness, Biomechanics, Energy storage, Vessels, Aorta
Journal Articles

Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study

Rachelle Walter, Kendall Hunter, Kurt Stenmark, Vitaly O. Kheyfets
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. February 2022, 144(2): 024503.
Paper No: BIO-20-1512
https://doi.org/10.1115/1.4051719
Published Online: September 30, 2021
View Article titled, Hemodynamically Unloading the Distal Pulmonary Circulation in Pulmonary Hypertension: A Modeling Study
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Topics: Engineering simulation, Hemodynamics, Modeling, Pressure, Shear stress, Simulation, Stress, Vessels, Lung, Flow (Dynamics)
Journal Articles

A Review on the Effect of Temporal Geometric Variations of the Coronary Arteries on the Wall Shear Stress and Pressure Drop

Navid Freidoonimehr, Rey Chin, Anthony Zander, Maziar Arjomandi
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. January 2022, 144(1): 010801.
Paper No: BIO-21-1073
https://doi.org/10.1115/1.4051923
Published Online: September 1, 2021
View Article titled, A Review on the Effect of Temporal Geometric Variations of the Coronary Arteries on the Wall Shear Stress and Pressure Drop
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Topics: Coronary arteries, Flow (Dynamics), Cardiac cycle, Vessels, Hemodynamics, Pressure drop