...Sarah K. Van Houten; Michael T. K. Bramson; David T. Corr Bioreactors are commonly used to apply biophysically relevant stimulations to tissue-engineered constructs in order to explore how these stimuli influence tissue development, healing, and homeostasis, and they offer great flexibility because...

... to repair due to their avascularity, and limited clinical repair and replacement options exist. Tissue engineering has been proposed as a route to repair and replace fibrocartilages. Using the knee meniscus and TMJ disc as examples, this review describes how fibrocartilages can be engineered toward...

...Shuo Zhang; Sanjairaj Vijayavenkataraman; Geng Liang Chong; Jerry Ying Hsi Fuh; Wen Feng Lu Nerve guidance conduits (NGCs) are tubular tissue engineering scaffolds used for nerve regeneration. The poor mechanical properties and porosity have always compromised their performances for guiding...

.... Mater. Res. , 27 , pp. 1165 – 1173 . 10.1002/jbm.820270907 [39] Setton , L. A. , Guilak , F. , Hsu , E. W. , and Vail , T. P. , 1999 , “ Biomechanical Factors in Tissue Engineered Meniscal Repair ,” Clin. Orthop. Relat. Res. , 367S , pp. 254 – 272 . 10.1097/00003086...

... to biomanufacturing of 3D functional cellular tissue engineering constructs for various organ systems. bioprinting cell-laden hydrogels vascular constructs tissue engineering For the past three decades, tissue engineering and regenerative medicine has emerged as a multidisciplinary field involving...

... water transport tissue engineering extracellular matrix Cryopreservation can provide long-term storage of various biological tissues, which has significant impact on tissue engineering and regenerative medicine. For successful cryopreservation of tissues, tissue functionality including...

... with efficient diffusion by increasing our understanding of how the diffusion rate within a scaffold is affected by its pore architecture. scaffold mass transport effective diffusivity computational simulation tissue engineering Scaffold-based tissue engineering is very promising in the field...

...Victor K. Lai; Spencer P. Lake; Christina R. Frey; Robert T. Tranquillo; Victor H. Barocas Fibrin and collagen, biopolymers occurring naturally in the body, are biomaterials commonly-used as scaffolds for tissue engineering. How collagen and fibrin interact to confer macroscopic mechanical...

... 21 12 2011 27 12 2011 21 12 2011 biological fluid dynamics bone cellular biophysics computational fluid dynamics micromechanics prosthetics tissue engineering Total hip replacement (THR) aseptic loosening osteolysis capsular pressure micromotion periprosthetic...

... subpopulations of hESCs. 03 12 2010 22 08 2011 07 11 2011 07 11 2011 atomic force microscopy biomechanics cellular biophysics elasticity tissue engineering Young's modulus embryonic stem cells elasticity Young’s modulus Matrigel fibroblast Human embryonic stem...

... compounds materials preparation porosity porous materials tissue engineering References 1 Elvitigala , T. R. , Polpitiya , A. D. , Wang , W. , Stöckel , J. , Khandelwal , A. , Quatrano , R. S. , Pakrasi , H. , and Ghosh , B. K. , 2010 , “ High...

...Tai-Yi Yuan; Chun-Yuh Huang; Wei Yong Gu The goal of tissue engineering is to use substitutes to repair and restore organ function. Bioreactors are an indispensable tool for monitoring and controlling the unique environment for engineered constructs to grow. However, in order to determine...

... 2011 11 10 2011 11 10 2011 biochemistry biological fluid dynamics bioreactors bone cellular biophysics foams macromolecules molecular biophysics orthopaedics porous materials proteins pulsatile flow tissue engineering mesenchymal stem cells PLGA pulsatile perfusion...

... bioceramics bone calcium compounds calibration cellular biophysics materials preparation mesh generation porosity tissue engineering Young's modulus tissue engineering bone scaffolds cellular solids geometry projection numerical homogenization micro-robotic deposition Natural...

...Kirsten R. C. Kinneberg; Marc T. Galloway; David L. Butler; Jason T. Shearn Previous studies by our laboratory have demonstrated that implanting a stiffer tissue engineered construct at surgery is positively correlated with repair tissue stiffness at 12 weeks. The objective of this study...

... towards controllable shear-induced erosion. biomechanics biomedical materials elastic constants permeability polymers tissue engineering wall shear stress topology optimization scaffold biofluid biodegradation As a fundamental premise of tissue engineering, scaffold is expected...

...Ana L. F. Soares; Maria Stekelenburg; Frank P. T. Baaijens Mechanical loading protocols in tissue engineering (TE) aim to improve the deposition of a properly organized collagen fiber network. In addition to collagen remodeling, these conditioning protocols can result in tissue compaction. Tissue...

...Cédric P. Laurent; Jean-François Ganghoffer; Jérôme Babin; Jean-Luc Six; Xiong Wang; Rachid Rahouadj Tissue engineering offers an interesting alternative to current anterior cruciate ligament (ACL) surgeries. Indeed, a tissue-engineered solution could ideally overcome the long-term complications...

... was developed to investigate cell-matrix interactions under unconfined compression conditions, using a tissue engineered encapsulating hydrogel seeded with chondrocytes. Model predictions of stress and strain distributions within the cell and on the cell boundary were shown to exhibit space-dependent responses...

... the transport of a relatively large neutral species (negligible osmotic fluid flux) in highly deformable hydrated soft tissues and tissue-engineered materials. In conclusion, an ABAQUS -based PHEXPT theory and finite element model has been presented, which will find application in a number of coupled species...