...Rayanne Pinto Costa; Blaise Simplice Talla Nwotchouang; Junyao Yao; Dipankar Biswas; David Casey; Ruel McKenzie; Frederick Sebastian; Rouzbeh Amini; David A. Steinman; Francis Loth Previous experimental flow studies have demonstrated a delay (∼20%) in transition to turbulence for whole blood...

...Rayanne Pinto Costa; Blaise Simplice Talla Nwotchouang; Junyao Yao; Dipankar Biswas; David Casey; Ruel McKenzie; David A. Steinman; Francis Loth Blood, a multiphase fluid comprised of plasma, blood cells, and platelets, is known to exhibit a shear-thinning behavior at low shear rates and near...

... with the theoretical values for the validation of the model. Finally, ten units ( 212.9 ml / unit ± 9.5 ml / unit ) of thawed human red blood cells (cryopreserved with 40% (w/v) glycerol) were deglycerolized using the theoretically optimal operation protocols to further validate the effectiveness and advantage...

... been observed to contain a mixture of blood cells, platelets, blood proteins, and cellular debris in a fibrin structure within porous, distinguishable layers. In observations by Wang et al., scanning electron microscopy indicated that the different layers had different underlying structures...

... for the concentration of an absorbed vapor in an air-mucus-tissue-blood (AMTB) model of the respiratory wall was developed for transient and variable air-phase concentrations. Based on the analytical expression, a flux boundary condition was developed at the air-mucus interface as a function of the far-field air-phase...

...Youhua Tan; Dong Sun; Wenhao Huang Mechanical properties of red blood cells (RBCs) play an important role in regulating cellular functions. Many recent researches suggest that the cell properties or deformability may be used as a diagnostic indicator for the onset and progression of some human...

... for implantable artificial organs or devices. When these materials are coated on vascular devices, compatibility to blood is an important problem. The present paper focuses on friction characteristics of erythrocytes to these coating materials in a medium. With an inclined centrifuge microscope developed...

...Sandra Rugonyi Transport of bioactive agents through the blood is essential for cardiovascular regulatory processes and drug delivery. Bioactive agents and other solutes infused into the blood through the wall of a blood vessel or released into the blood from an area in the vessel wall spread...

...Toru Hyakutake; Shouko Tominaga; Takeshi Matsumoto; Shinichiro Yanase Flow analysis at microvascular bifurcation after partial replacement of red blood cell (RBC) with liposome-encapsulated hemoglobin (LEH) was performed using the lattice Boltzmann method. A two-dimensional symmetric Y bifurcation...

...Kit Yan Chan; Hideki Fujioka; Ronald B. Hirshl; Robert H. Bartlett; James B. Grotberg The pulsatile blood flow and gas transport of oxygen and carbon dioxide through a cylindrical array of microfibers are numerically simulated. Blood is modeled as a homogeneous Casson fluid, and hemoglobin...

... diseases biological tissues cellular biophysics blood numerical analysis Particles of different sizes, shapes, and traits circulate inside the anterior chamber of the eye. Examples of such particles include pigment particles, protein particles (albumin), erythrocytes, and leukocytes...

... in Marrow Culture ,” J. Cell Physiol. 0021-9541 10.1002/(SICI)1097-4652(199701)170:1<81::AID-JCP9>3.3.CO;2-L , 170 ( 1 ), pp. 81 – 87 . cellular biophysics biomechanics computational fluid dynamics blood bone mechanobiology progenitor cells mechanical stimulation bioreactor...

... interpretation of Giersiepen-Wurzinger blood damage correlation as a volume integration of a damage function over the computational domain. We now propose an improvement of this approach based on a hyperbolic equation of blood damage that is asymptotically consistent. Consequently, while the proposed correction...

...Prosenjit Bagchi; Paul C. Johnson; Aleksander S. Popel We present computational fluid dynamic (CFD) simulation of aggregation of two deformable cells in a shear flow. This work is motivated by an attempt to develop computational models of aggregation of red blood cells (RBCs). Aggregation of RBCs...

... of convection, a single terminal alveolar sac is modeled as an oscillating spherical shell with gas, PFC, tissue and capillary blood compartments. Differential equations describing mass conservation within each compartment are derived and solved to obtain time periodic partial pressures. Significant partial...

... rotational flow cardiology haemodynamics blood cellular biophysics PIV Wall Shear Rate Artificial Heart Clot formation within an artificial heart is a major problem of device performance after implantation 1 2 3 . We hypothesize a strong connection between clot deposits on the sac wall...

... 12 2002 oxygen solutions blood bubbles blood vessels nucleation biomedical engineering This paper describes a strategy for the rapid delivery of large quantities of dissolved oxygen to the bloodstream without the formation of oxygen gas bubbles. The potential method benefits...

... of the lungs. The simulations, mimicking the single-breath technique for measuring the lung diffusing capacity for carbon-monoxide (CO), allow the prediction of the red blood cell (RBC) distribution effects on the lung diffusing capacity. Results, obtained through numerical simulations, unveil a strong...

...Jin-Yu Shao; Jinbin Xu Tether formation, which is mechanically characterized by its threshold force and effective viscosity, is involved in neutrophil emigration from blood circulation. Using the micropipette aspiration technique, which was improved by quantitative contact control and computerized...

...S. Q. Liu; L. Zhong; J. Goldman Fluid mechanical factors are thought to influence vascular morphogenesis. Here we show how blood shear stress regulates the shape of a thrombus-neointima-like tissue on a polymer micro-cylinder implanted in the center of the rat vena cava with the micro-cylinder...