... variety of nonlinear elastic and inelastic properties. Such complicated properties of cells are known to emerge from unique mechanical characteristics of cellular components. In this review, we introduce major cellular components that largely govern cell mechanical properties and provide brief...

... factor algorithm to experimental TFM measurements in invasive and noninvasive cancer cells. Therefore, application of these types of corrections to TFM measurements can yield more accurate estimates of cell contractility. cell contractility cell mechanics cell adhesion strain hardening cancer...

... is ∼ 0.05   s ( 2 ), so that AVICs apparently undergo very high strain rates. viscoelasticity cell mechanics micropipette aspiration heart valves biological tissues biomechanics cardiovascular system cellular biophysics creep deformation stress relaxation viscoelasticity...

... cochlear electrochemical gradients into mechanical forces. This allows the cochlear partition to overcome the viscous damping and ultimately provide the amplification and sharp frequency selectivity of the ear ( 1 2 3 ). bending cytoskeleton adhesion elastic shell model active hearing cell...

... surface tension viscosity three-dimensional modeling of cells finite element method cell mechanics partial engulfment Young’s angle Because in silico methods have the power to elucidate causal connections in complex systems ( 1 2 ), they are an essential resource...

... experiments. The correlation of the mechanical behavior of the cell with the cell composition, as obtained through this study, is an important observation in cell mechanics. 02 05 2006 19 11 2006 cellular biophysics biomechanics finite element analysis atomic force microscopy...

... intracellular transport microrheology mitochondria chondrocytes cell mechanics Motion of intracellular organelles is fundamental to cellular function. Cellular organelles undergo constant motion and redistribute in response to changing physiological conditions ( 1 2 ). Different organelles display...

... force microscopy elastic moduli fluorescence cell mechanics stress fibers actin cytoskeleton Nanoindentation with an atomic force microscope (AFM) is a relatively straightforward method for probing the mechanical properties of a wide variety of materials ( 1 2 3 ). Because it enables...

... biomechanics compressibility deformation blood vessels silicones bone orthopaedics Cell Mechanics Stretching Compression Stress Fibers Endothelial cells lining blood vessels are subjected to several different types of mechanical stimuli including hydrostatic pressure, fluid shear stress...

... May 2004 01 June 2004 23 11 2004 proteins adhesion nucleus cellular biophysics cellular transport Cell Mechanics Mechanics of the Nucleus Cytoskeletal Forces Endothelial Cells Cells of all types are constantly being exposed to external forces within...

... and spread morphology of the cells. Thus far, cell mechanical properties have been studied using a range of experimental techniques that can roughly be divided into two distinct groups: (i) techniques for global loading of individual cells, such as microplate manipulation ( 4 5 ), micromanipulation ( 6...

... manuscript received May 2002. Associate Editor: T. C. Skalak. 01 July 1999 01 May 2002 30 09 2002 cellular biophysics biomechanics boundary-elements methods biological techniques physiological models boundary integral equations Cartilage Osteoarthritis Cell Mechanics...

... understanding of the physical world. The merit of such theories lies in their simplicity and in their ability to reliably predict a broad range of outcomes. Cell Mechanics Cell Sorting Cell Mixing Checkerboard Patterns Tissue Engulfment Computer Simulations Finite Element Method...

... biomechanics Shear Stress Smooth Muscle Cell Cell Mechanics Cell Alignment Vascular cells are arranged in distinct patterns in the multiple layers of the arterial wall with vascular smooth muscle cells (SMC) primarily aligned circumferentially in the media and endothelial cells (EC) oriented...

... Division December 27, 1999; revised manuscript received February 6, 2000. Associate Technical Editor: R. Vanderby, Jr. 27 December 1999 06 February 2000 viscoelasticity physiological models cellular biophysics biorheology Cartilage Osteoarthritis Cell Mechanics Chondrocyte...