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Christopher G. Rylander
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Journal Articles

Solid Fiber Inside of Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices for Improved Light Transmission Efficiency

Jason N. Mehta, Brianna E. Morales, John H. Rossmeisl, Waldemar Debinski, Christopher G. Rylander
Journal: Journal of Medical Devices
Article Type: Research-Article
J. Med. Devices. December 2022, 16(4): 041014.
Paper No: MED-22-1049
DOI: https://doi.org/10.1115/1.4055607
Published Online: September 27, 2022
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Topics: Fibers, Microneedles, Manufacturing
Journal Articles

Constant Pressure Convection-Enhanced Delivery Increases Volume Dispersed With Catheter Movement in Agarose

Jason N. Mehta, Brianna E. Morales, Fang-Chi Hsu, John H. Rossmeisl, Christopher G. Rylander
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2022, 144(11): 111003.
Paper No: BIO-21-1376
DOI: https://doi.org/10.1115/1.4054729
Published Online: June 16, 2022
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Topics: Agar, Catheters, Flow (Dynamics), Pressure, Convection
Proceedings Papers

Burst, Leakage, and Constant Pressure Infusion Testing of a Convection Enhanced Drug Delivery System for Glioblastoma Treatment

Iman Salafian, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T10A006, April 11–14, 2022
Paper No: DMD2022-1060
DOI: https://doi.org/10.1115/DMD2022-1060
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Topics: Catheters, Convection, Drug delivery systems, Fibers, Flow (Dynamics), Food and Drug Administration, Frequency-domain analysis, Leakage, Microneedles, Pressure
Proceedings Papers

Evaluating The Dispersal Volume of a Six-Port Arborizing Catheter in Agarose as a Function of Infusion Flow Rate and Catheter Retraction Speed

Etse-Oghena Y. Campbell, Fang-Chi Hsu, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T10A005, April 11–14, 2022
Paper No: DMD2022-1057
DOI: https://doi.org/10.1115/DMD2022-1057
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Topics: Agar, Catheters, Convection, Flow (Dynamics)
Proceedings Papers

Convection-Enhanced Thermo-Therapy Catheter System: Microneedle Compression Strength Testing with Various Durometers

Brianna E. Morales, Christopher G. Rylander
Proc. ASME. DMD2022, 2022 Design of Medical Devices Conference, V001T05A007, April 11–14, 2022
Paper No: DMD2022-1067
DOI: https://doi.org/10.1115/DMD2022-1067
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Topics: Catheters, Compressive strength, Convection, Microneedles, Patient treatment, Testing
Proceedings Papers

Measuring Line Pressure in Convection-Enhanced Delivery Infusions

Jason N. Mehta, Brianna E. Morales, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A012, April 12–15, 2021
Paper No: DMD2021-1083
DOI: https://doi.org/10.1115/DMD2021-1083
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Topics: Convection, Pressure
Proceedings Papers

Helical Needle Suture Inserter Provides Increased Suture Retention Force Compared to a Straight Needle

Etse-Oghena Y. Campbell, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A016, April 12–15, 2021
Paper No: DMD2021-1089
DOI: https://doi.org/10.1115/DMD2021-1089
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Topics: Biological tissues, Needles, Phantoms
Proceedings Papers

Computational Model of a Two Material Object Predicts Non-Symmetric Dispersal Volume Profile

Brianna E. Morales, Jason N. Mehta, Christopher G. Rylander
Proc. ASME. DMD2021, 2021 Design of Medical Devices Conference, V001T12A014, April 12–15, 2021
Paper No: DMD2021-1087
DOI: https://doi.org/10.1115/DMD2021-1087
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Topics: Computer simulation, Convection, Microneedles
Journal Articles

Convection-Enhanced Arborizing Catheter System Improves Local/Regional Delivery of Infusates Versus a Single-Port Catheter in Ex Vivo Porcine Brain Tissue

Egleide Y. Elenes, Jason N. Mehta, Fang-Chi Hsu, Christopher T. Whitlow, Waldermar Debinski, John Rossmeisl, Stephen Tatter, Christopher G. Rylander
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Article Type: Research-Article
ASME J of Medical Diagnostics. February 2021, 4(1): 011003.
Paper No: JESMDT-20-1011
DOI: https://doi.org/10.1115/1.4048935
Published Online: December 2, 2020
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Topics: Biological tissues, Brain, Catheters, Microneedles, Convection
Proceedings Papers

Solid Fiber Inside Capillary and Modified Fusion-Spliced Fiber Optic Microneedle Devices

Jason N. Mehta, Christopher G. Rylander
Proc. ASME. DMD2020, 2020 Design of Medical Devices Conference, V001T10A010, April 6–9, 2020
Paper No: DMD2020-9050
DOI: https://doi.org/10.1115/DMD2020-9050
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Topics: Fibers, Microneedles, Lasers, Manufacturing, Brain, Failure, Fluids, Catheters, Convection, Drug delivery systems
Proceedings Papers

Novel Method and Device for Delivery and Retention of Intrauterine Devices in the Immediate Postpartum Period: Pilot Baboon Feasibility Study

Etse-Oghena Campbell, Christopher G. Rylander, Lauren Thaxton, Marian Yvette Williams-Brown
Proc. ASME. DMD2020, 2020 Design of Medical Devices Conference, V001T10A009, April 6–9, 2020
Paper No: DMD2020-9049
DOI: https://doi.org/10.1115/DMD2020-9049
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Topics: Safety
Journal Articles

Parametric Study of the Design Variables of an Arborizing Catheter on Dispersal Volume Using a Biphasic Computational Model

Egleide Y. Elenes, Manuel K. Rausch, Christopher G. Rylander
Journal: Journal of Engineering and Science in Medical Diagnostics and Therapy
Article Type: Research-Article
ASME J of Medical Diagnostics. August 2019, 2(3): 031002.
Paper No: JESMDT-18-1066
DOI: https://doi.org/10.1115/1.4042874
Published Online: April 1, 2019
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Topics: Agar, Biological tissues, Catheters, Cavities, Convection, Design, Flow (Dynamics), Gates (Closures), Pressure, Simulation
Proceedings Papers

Mechanical Compression for Dehydration and Optical Clearing of Skin

Chris W. Drew, Christopher G. Rylander
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 803-804, June 25–29, 2008
Paper No: SBC2008-193017
DOI: https://doi.org/10.1115/SBC2008-193017
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Topics: Biological tissues, Compression, Electromagnetic scattering, Fibers, Light scattering, Proteins, Radiation scattering, Refractive index, Scattering (Physics), Skin
Journal Articles

Influence of Hyperthermia on Efficacy and Uptake of Carbon Nanohorn-Cisplatin Conjugates

Matthew R. DeWitt, Allison M. Pekkanen, John Robertson, Christopher G. Rylander, Marissa Nichole Rylander
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021003.
Paper No: BIO-13-1471
DOI: https://doi.org/10.1115/1.4026318
Published Online: February 5, 2014
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Topics: Carbon, Drugs, Heat, Nanoparticles, Tumors, Temperature, Heating, Particulate matter, Patient treatment, Diffusion (Physics)
Proceedings Papers

Coupled Poroviscoelastic and Optical Monte Carlo Simulation of Dynamic Light Transport Through Indented Soft Tissue

William C. Vogt, Christopher G. Rylander
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT36A004, June 26–29, 2013
Paper No: SBC2013-14683
DOI: https://doi.org/10.1115/SBC2013-14683
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Topics: Absorption, Biological tissues, Compression, Deformation, Electromagnetic scattering, Flow (Dynamics), Fluid dynamics, Proteins, Radiation scattering, Refractive index
Proceedings Papers

Increased Light Transport in Skin Using Mechanical Compression

Chris W. Drew, Alondra Izquierdo-Roman, Yajing Liu, Christopher G. Rylander
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 353-354, June 17–21, 2009
Paper No: SBC2009-206628
DOI: https://doi.org/10.1115/SBC2009-206628
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Topics: Compression, Skin, Biological tissues, Light scattering, Water, Electromagnetic scattering, Fibers, Proteins, Radiation scattering, Refraction
Proceedings Papers

Fiberoptic Microneedle Probes for Tissue Penetration

Mehmet A. Kosoglu, Christopher G. Rylander
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 497-498, June 17–21, 2009
Paper No: SBC2009-206742
DOI: https://doi.org/10.1115/SBC2009-206742
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Topics: Biological tissues, Microneedles, Probes, Lasers, Absorption, Biomedicine, Coherence (Optics), Electromagnetic scattering, Imaging, Patient treatment
Proceedings Papers

Fluorescently Labeled Carbon Nanohorns as Intracellular Drug Delivery Vehicles

Kristen A. Zimmermann, David Inglefield, Timothy E. Long, Christopher G. Rylander, M. Nichole Rylander
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 635-636, June 20–23, 2012
Paper No: SBC2012-80818
DOI: https://doi.org/10.1115/SBC2012-80818
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Topics: Carbon, Drug delivery systems, Vehicles, Nanomaterials, Anticancer drugs, Biomedicine, Drugs, Lasers, Patient treatment, Shapes
Proceedings Papers

A Nondestructive Fiber-Based Imaging System to Assess Tissue-Engineered Vascular Grafts

Bryce M. Whited, Matthias C. Hofmann, Peng Lu, Christopher G. Rylander, Shay Soker, Ge Wang, Yong Xu, Marissa Nichole Rylander
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 493-494, June 20–23, 2012
Paper No: SBC2012-80298
DOI: https://doi.org/10.1115/SBC2012-80298
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Topics: Biological tissues, Bioreactors, Blood flow, Endothelial cells, Fibers, Fibroblasts, Imaging, Muscle, Synthetic products, Tissue engineering
Proceedings Papers

Improving Convection-Enhanced Delivery Through Photothermal Augmentation of Fluid Dispersal

R. Lyle Hood, Tobias Ecker, John Rossmeisl, John Robertson, Christopher G. Rylander
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 263-264, June 20–23, 2012
Paper No: SBC2012-80720
DOI: https://doi.org/10.1115/SBC2012-80720
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Topics: Convection, Fluids, Tumors, Brain, Cancer, Blood, Catheters, Drugs, Food and Drug Administration, Frequency-domain analysis